Rimonabant is a representative of new anti-obesity class drugs that act on endocannabinoid system of the body. This system takes part in regulation of body temperature, activity of endocrine system, the blood pressure and controls the consumption as well as digestion of food.
The study, called STRATUS (Studies with Rimonabant and Tobacco Use) has confirmed the real benefits of Rimonabant tablets on smokers. First of all, the drugs really helps to deal with nicotine dependence and get rid of this bad habit.
After smoking cessation, many former smokers start gaining extra weight. Rimonabant tablets help them to control the appetite, due to which the body mass does not increase
According to the data, Rimonabant tablets double the likelihood of smoking cessation in patients, using the drug, rather than in those, who took placebo.
During RIO-Europe clinical study, scientists revealed that Rimonabant 20 mg tablets increased the insulin sensitivity and reduced the levels of leptin and glucose in the blood.
As a result, obese patients, using Rimonabant within 2 years, managed to lose about 20% of their initial body weight and 7.8 cm of their waist size.
However, in 2008, Rimonabant tablets were withdrawn from the pharmaceutical markets in many countries of the world. The reason was other studies that had established that the risks outweighed Rimonabant tablets benefits.